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My main source for this video was the textbook Cellular and Molecular Immunology by Abul Abbas, Andrew Lichtman & Shiv Pillai. I'll do a deep dive livestream for this piece soon and post a link here when I do!
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----LYRICS---
Cause I I I got the SARS tonight
So watch me ring up my blood cells of white
First up
Coming through the blood
Neutrophil come slow your roll
Eat up micro bods
Gummed up when your guts explode
Hang tight waiting monocyte
Hulk out til you're chowing em down
Signals from my killer cells
And those weak and infected go "blao"
This is getting heavy
Better get the lymph nodes all ready
Got a fever running
And these signal cytokines flooding
Defense overrun
we need to send a sample on
Dendritic, you gotta go off
so let's go!
Cause I I I got the SARS tonight
So watch me bring peptides to the meeting site
Fly into the lymph node with the details of the bug
So I can fight it off by leukocyte
Bring a friend, join the crowd
Together filling up the node
New white lymphocytes
Of the thymus and the bone
Scatter-gun, million-to-one
Which ones are compatible?
"Ladies and gentlemen
I got the antigen
So you can keep your eyes on the ball"
This is getting heavy
Can we get T's trained already
Helping, teaching, gunning
Plasma cells with antibods flooding
These made optimal
We need to save a sample of
Archive em, y'all others go off
And let's go
Cause I I I got the SARS tonight
So watch me bring trained cells to the battle site
Target a specific set of features of the bug
So I can fight it off by leukocyte
Slide through the side to find the right site of the fight
Fight it leukocyte
Fly like a guided viricide bind to the site
Fight it leukocyte
Target cells exhibiting a feature of the bug
So I can fight it off by leukocyte
Die for the tribe deny the shock play
Try and imbibe a fly-by-night prey
Pry, nullify the viral home bay
Fight it off leukocyte
Spy to provide a vital dossier
Vie to supply the binding Y shape
Scry, then apply a cytokine aide
Fight it off leukocyte
Cause I I I got the SARS tonight
So watch me bring all guns to the firefight
Target tainted tissue with a team to SWAT the bug
So I can fight it off by leukocyte
Cause I I I got the SARS tonight
So watch me bring the fire to the parasite
Integrated synergy to seek and squash the bug
So I can fight it off by leukocyte
Guide what survived to multiply righting the blight
Right it leukocyte
Time to resign, the high supply cost to requite
Bite it leukocyte
But I will keep this memory with features of the bug
So I can fight it off by leukocyte